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Polynucleotides london


Polynucleotides, at the forefront of anti-ageing, offer a promising way to maintain youthfulness, drawing interest from medical and cosmetic fields.


  • Promotes natural regeneration
  • Minimal discomfort
  • Non-invasive procedure

What are Polynucleotides?

Polynucleotides are long chains of nucleotides, which are the basic components of DNA and RNA. 


These molecules are known for their regenerative abilities, boosting skin rejuvenation at a cellular level by increasing collagen and elastin production. These proteins are essentials for maintaining skin structure and elasticity, which tend to decrease with age.

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Benefits of Polynucleotide Treatments

Polynucleotide treatments at PHI Clinic enhance skin hydration, elasticity, and firmness by activating internal processes, offering a natural alternative to traditional fillers. These treatments stimulate collagen production, improving overall skin appearance.

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Polynucleotide treatments in London Clinic

Polynucleotide treatments at PHI Clinic provide a holistic approach to skin rejuvenation, addressing volume loss, fine lines, stretch marks, and skin tone irregularities through natural regeneration. Administered with utmost care, these treatments promote rejuvenated skin and improved structure for lasting results.


The initial consultation is important to evaluate the skin health and setting realistic expectations. It begins with a professional assessment of skin condition and goals, followed by a detailed analysis to determine treatment suitability and create a tailored plan based on individual skin needs. Before injections, a topical anaesthetic minimises discomfort, and precise administration of polynucleotides stimulates collagen and elastin production for enhanced skin elasticity and texture. 


Patients are monitored for immediate side effects post-treatment and provided with recovery guidelines, allowing most to resume daily activities shortly after. Post-treatment recovery guidance includes care instructions for optimal outcomes, with follow-up appointments ensuring progress monitoring. 

Where on the face can you have Polynucleotide?

Typically, polynucleotide treatments target facial areas susceptible to signs of ageing, such as fine lines, wrinkles, and diminished elasticity. These key treatment zones include the cheeks, forehead, around the eyes (crow's feet), and areas affected by scars or pigment irregularities. Additionally, Polynucleotide treatments can be used on the body for specific rejuvenation purposes, targeting areas where skin texture, firmness, or hydration needs improvement.


Are Polynucleotide treatments better than Profhilo?

When comparing Polynucleotide treatments to Profhilo, both offer distinct benefits in skin rejuvenation. Polynucleotides excel in enhancing skin hydration, elasticity, and firmness through their regenerative properties, stimulating natural collagen production. They target specific ageing concerns such as fine lines, wrinkles, and uneven skin tone, providing a comprehensive approach to skin revitalisation


On the other hand, Profhilo focuses on improving overall skin hydration and firmness with a unique hyaluronic acid formulation, promoting deep tissue hydration and remodelling. The choice between these treatments often depends on individual skin goals and preferences for either collagen stimulation or intense hydration.


When do Polynucleotide treatments show results, and are there any side effects?

Polynucleotide treatments typically show initial results within a few weeks to a month, depending on individual skin response. These treatments activate natural skin processes, stimulating collagen and elastin production for improved hydration and firmness over time. As for side effects, minor redness, swelling, or bruising at the injection sites may occur temporarily. These effects usually resolve within a few days post-treatment, ensuring a smooth recovery process.

Safe and effective treatment

Your safety is our top priority and making our patients feel welcomed and reassured when entering PHI Clinic. To ensure maximum standard of patient care, all of our treatments are only ever carried out by our experienced and highly qualified team, who receive regular in-house and external training from industry experts. 

At PHI Clinic we do not offer same day treatment as initial consultation to ensure patients have time to reflect on their bespoke treatment plan before choosing to proceed. 

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Polynucleotide frequently asked questions


PHI Clinic
102 Harley Street,
W1G 7JB,
United Kingdom

Tel: +44 7883 317963

Opening Hours

Monday & Tuesday - 9:30am to 6:00pm
Wednesday & Thursday - 9:30am to 8:00pm
Friday - 9:30am to 5:30pm
Saturday & Sunday - Closed

Opening times can change, if your appointment is outside of these times please contact the clinic for confirmation.