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What Makes Polynucleotides Different?
Polynucleotides are chains of nucleotides, the building blocks of DNA and RNA, derived from purified salmon DNA. When injected into the skin, they support skin regeneration by stimulating tissue repair, calming inflammation, enhancing skin hydration, and preventing the breakdown of collagen and elastin.
At PHI Clinic, we use polynucleotides in London to treat a wide range of skin problems and concerns, including:
- Under-eye hollows, crepey skin and dark circles
- Dull skin and dry skin
- Fine lines, deep lines, and wrinkles
- Acne scars and stretch marks
- Sun-damaged skin and mature skin
- Skin texture concerns, pigmentation and uneven skin tone
These injectable skin boosters are especially effective for sensitive skin and delicate areas like the tear troughs and neck, where other cosmetic procedures might be too harsh.
When Will I See Results?
Polynucleotides work gradually by supporting natural cell regeneration. You may start to see subtle, visible improvements in skin glow, texture, and hydration around 3 to 4 weeks after your initial treatment session.
Typical early signs of progress include:
- Improved skin tone and skin elasticity
- A fresher, more youthful appearance
- Visible wrinkle reduction
- Calmer, healthier skin overall
These aesthetic treatments are designed to provide a natural, youthful glow, not a dramatic overnight transformation.
Why a Course of Treatments Is Recommended
For optimal rejuvenating effects, polynucleotide injections in London are administered as a course of 3 to 4 treatment sessions, spaced 2 to 4 weeks apart. Each polynucleotide session helps stimulate fibroblast cells and collagen production for long-term results.
Think of it as skin rehabilitation, a regenerative rather than resurfacing approach with minimal side effects.
What to Expect After Completing the Course
Around 8 to 12 weeks after your final session, the regenerative benefits are at their fullest. Most patients report:
- Smoother skin and enhanced hydration
- Reduction in fine lines and crepey skin
- A more radiant, youthful skin appearance
- Greater skin resilience and improved elasticity
The subtle, cumulative results are particularly popular among patients with textured skin, dullness, and an aged appearance who want natural-looking outcomes without invasive cosmetic treatments.
How Long Do Polynucleotide Results Last?
With a full course, the results of this aesthetic procedure typically last 6 to 9 months. Maintenance treatments every 6 months can prolong the effects, especially for the under-eyes.
This makes polynucleotides a skin-quality treatment not just for correction, but also as part of a preventative skincare routine.
Do All Patients Respond the Same Way?
Every patient's skin is different, and responses vary based on factors such as:
- Age and collagen levels
- Medical history and circulatory disorders
- Active skincare routine
- Skin type, sun exposure, and skin hydration
Some patients notice a glow within days, while others see gradual, steady improvement across the weeks after treatment. At PHI Clinic, we build every treatment plan around a skin assessment, taking into account your concerns, skin condition, and aesthetic goals.
What Happens During Treatment?
The initial treatment involves injecting the polynucleotides into the skin using fine needles. A topical numbing cream is usually applied first, and most people find any discomfort mild and short-lived.
Afterwards, small bumps, mild swelling, bruising or redness may appear at the injection sites, especially in the delicate periorbital area. These usually resolve within 24 hours, and downtime is minimal.
Aftercare matters more than most people expect. Our post-treatment instructions are simple:
- Drink plenty of water
- Avoid direct sun exposure and apply SPF
- Use gentle active ingredients in your skincare routine
Why Choose PHI Clinic London for Polynucleotides?
At PHI Clinic, we use high-grade polynucleotide injectables in London. Our team is trained in combining polynucleotides with energy-based treatments, such as microneedling and laser resurfacing, for more noticeable results.
We frequently pair these injectables with:
- iS Clinical skincare to maintain skin health
- Anti-wrinkle injections, sometimes known as Botox, where expression lines are part of the picture
- Dermal fillers where there is loss of volume or deeper lines
Whether you're managing sensitive skin, acne-related redness, or signs of ageing, we create a personalised treatment plan designed to deliver healthier skin with visible improvements.
A Quick Summary: The Polynucleotide Timeline
- Initial glow: 3 to 4 weeks after treatment
- Fullest results: 8 to 12 weeks following your final session
- Longevity: 6 to 9 months, with optional maintenance treatments
If you're looking for a professional treatment with minimal downtime and natural results, polynucleotides offer a considered route to skin rejuvenation and long-lasting repair.
Book a Consultation at PHI Clinic
Ready to find out if polynucleotides at our London clinic are right for you? Book your consultation at PHI Clinic and our team will talk you through a personalised treatment plan, including how many sessions you are likely to need and the cost of treatment.
