Medically reviewed by Dr Tapan Patel
Last reviewed: 22nd February 2026
Profhilo treatment
Profhilo treatment at our London clinic tightens skin from within, giving excellent anti-ageing results for both face and body. It firms up sagging and crepey skin, reduces the appearance of crow's feet, smooths frown lines and forehead lines, hydrates the skin and gives a refreshed, healthy glow. It is a quick, safe and effective anti-ageing treatment, and is FDA approved for treating skin laxity.
Profhilo injections contain hyaluronic acid, similar to traditional dermal fillers, but with a key difference. While other fillers restore lost volume, Profhilo works by stimulating the body’s own collagen and elastin production, remodelling skin in a natural and discreet way. This makes Profhilo an ideal treatment for combating several signs of ageing such as wrinkles and sagging skin.
The treatment comes in two forms: the original Profhilo face treatment and the new Profhilo Body treatment.
What is Profhilo?
Profhilo is a unique injectable that uses hyaluronic acid in a slow release formula to target the layer of skin responsible for producing types of collagen. Unlike traditional dermal fillers, Profhilo doesn’t add volume but remodels skin from within, improving elasticity, hydration, and firmness.
The treatment is particularly effective for addressing wrinkled skin, including fine lines, crow’s feet, and nasolabial folds, and for restoring a radiant skin appearance. Its hydrating effects have earned it the nickname of an “injectable moisturiser,” as it works to deeply hydrate and plump dehydrated skin.
Profhilo benefits
Profhilo, which is suitable for men and women, is a revolutionary treatment that delivers exceptional benefits for improving skin condition and addressing the visible signs of ageing. By stimulating the production of collagen and elastin, it provides long-term results that enhance both skin health and appearance. This advanced injectable deeply hydrates the skin, creating a luminous finish while smoothing fine lines and reducing loose skin. Additionally, it improves skin tone and texture, offering a natural boost to your complexion without adding volume or altering your facial features.
Patients often experience a noticeable skin glow and increased elasticity, with results that are both discreet and transformative. Profhilo works with your skin’s natural processes to deliver a youthful appearance that looks refreshed and rejuvenated. With no obvious signs of treatment, you can enjoy a radiant, well-rested look that feels as good as it appears. Many chose this injectable moisturising treatment before their wedding to achieve a beautiful regenerated look.
Profhilo face treatment
At PHI Clinic, our Profhilo treatment for the face is expertly designed to tackle mild skin laxity, dehydration, and visible signs of ageing, leaving your skin firmer, smoother, and more radiant. This innovative injectable uses a slow-release hyaluronic acid formula that deeply hydrates and stimulates the production of collagen and elastin. By targeting the layer of skin responsible for elasticity and hydration, Profhilo enhances your overall skin quality without adding volume or altering your natural facial structure.
The treatment involves 10 precise injection points strategically placed to deliver the Profhilo formula beneath the skin. Once injected, the gel disperses naturally, requiring no massage and leaving no lumps or nodules. This unique approach promotes even hydration across the face, tackling common concerns such as:
• Lines around the mouth and wrinkles around the eyes, lips, and forehead
• Wrinkled skin, including crow’s feet and lip lines
• Loose skin and laxity in areas like the cheeks, jowls, and neck
With visible results after just two sessions spaced four to six weeks apart, Profhilo fits seamlessly into your routine and requires no downtime. Whether you’re addressing signs of ageing or enhancing hydration for a luminous skin finish, this treatment offers a safe and effective solution for achieving youthful, rejuvenated skin.
Profhilo Body
The revolutionary Profhilo Body treatment extends the benefits of Profhilo to areas of the body affected by skin laxity and dehydrated skin, such as:
- Hands
- Knees
- Abdomen
- Décolletage
- Neck
By targeting loose skin and wrinkled skin, Profhilo Body enhances elasticity, hydration, and overall skin condition. The treatment is complemented by a body patch and cream for use at home, ensuring optimal results between sessions. With us at PHI Clinic London Profhilo Body typically involves 2-3 sessions 4-6 weeks apart. It can be used alone or in combination with other treatments for skin tightening such as radio-frequency.
Who will perform my Profhilo treatment
At PHI Clinic, your safety and comfort are our top priorities. This treatment is provided by our highly trained doctors and nurses at our London Clinic PHI Clinic. From your initial consultation to the final results, we take a tailored approach to meet your unique needs, beginning with a detailed assessment to create a personalised treatment plan.
Your journey typically involves two to three treatment sessions, spaced four to six weeks apart, to achieve optimal results. We also provide thorough aftercare advice to help maximise the effects of your treatment while minimising any side effects, ensuring a seamless and comfortable experience from start to finish.
Your Profhilo practitioners
Safe and effective treatment
Your safety is our priority at PHI Clinic. All Profhilo treatments for both face and body are carried out by our team of fully qualified and highly experienced doctors who specialise in Profhilo treatments. Profhilo is injected at specific treatment points, typically during 2-3 sessions spaced 4-6 weeks apart. All our patients have a thorough consultation before having Profhilo, and treatment is always carried out on a separate day.
We believe it is essential for patients to be able to think before deciding whether to go ahead with their bespoke Profhilo treatment plan.
How long does Profhilo last?
The results of Profhilo can last up to six months, offering long-lasting improvements in skin quality, elasticity, and hydration. The exact duration depends on factors such as your skin type, age, lifestyle, and the customised treatment plan designed for your needs. For sustained benefits, it is recommended to schedule maintenance treatments every six to twelve months, ensuring your skin remains rejuvenated, firm, and radiant over time. Key considerations for maintaining your results:
- Consistency matters: Regular follow-up treatments help prolong the effects, keeping skin tone even and reducing the reappearance of loose skin or fine lines.
- Tailored plans: Your practitioner will assess your progress and recommend a maintenance schedule based on your individual response to the treatment.
- Enhancing longevity: Complement Profhilo with a healthy skincare routine, adequate hydration, and protection from UV exposure to further optimise results.
By adhering to a personalised treatment plan and periodic maintenance sessions, you can enjoy smooth, hydrated, and youthful skin all year round.
Aftercare Advice
After your Profhilo treatment, follow these simple guidelines to protect your skin and enhance your results:
- Avoid touching the treated area for six hours.
- Refrain from wearing makeup during this time.
- Avoid strenuous exercise, saunas, and UV exposure for 24 hours.
- Some patients may experience mild swelling or bruising, which typically subsides within a few days.
Profhilo frequently asked questions
Profhilo is a cutting-edge injectable treatment made from pure, high-grade hyaluronic acid. Unlike traditional fillers, it is not crosslinked, meaning it disperses naturally into the dermal cells, stimulating the production of collagen and elastin to improve skin elasticity and firmness. This unique formula deeply hydrates the skin, tackling tired, dull-looking skin and promoting a smoother, healthier texture. As an aesthetic treatment, Profhilo is ideal for enhancing overall skin quality, delivering natural and rejuvenating skin benefits without altering facial volume.
Profhilo is a highly versatile injectable skin treatment designed to address mild skin laxity, dehydration, and reduced skin elasticity across various areas of the body. It is particularly effective for the face, where it smooths fine lines, boosts hydration, and enhances skin firmness. On the neck and décolletage, Profhilo works to tighten and rejuvenate delicate skin prone to sagging. For areas such as the hands, knees, arms, and abdomen, it restores hydration and improves the appearance of tired, dull-looking skin and loose skin. By stimulating dermal cells responsible for collagen production, Profhilo delivers long-lasting improvements in skin quality, leaving it revitalised and refreshed.
Profhilo involves injections into 10 specific points per treatment area using very fine needles, making it a quick and effective treatment. Most patients describe the sensation as a mild scratch or sting that lasts only moments. For added comfort, a numbing cream can be applied before your treatment time, ensuring the process is as comfortable as possible. While some patients may experience slight swelling or redness hours after treatment, these effects are temporary and subside within a few days of treatment, allowing you to resume your daily routine immediately.
Profhilo is an FDA-approved anti-ageing treatment recognised for its safety and effectiveness. Its unique formula works naturally with your body, promoting hydration and skin elasticity without altering facial contours. Unlike traditional fillers, Profhilo’s rapid dispersal eliminates the risk of lumps or nodules. Although rare, mild side effects like slight swelling, redness, or bruising may occur, resolving within a few days. As a precaution, Profhilo is not suitable for those with certain medical conditions or a history of allergic reactions to hyaluronic acid. At PHI Clinic, all treatments are performed by experienced professionals, ensuring optimal care and safety.
Profhilo’s results can last up to six months, depending on your skin type, lifestyle, and the degree of skin laxity being treated. A standard course involves two sessions spaced four to six weeks apart, with some patients requiring a third session for enhanced results. For continued benefits, maintenance treatments every six to twelve months are recommended to sustain improvements in hydrated skin, elasticity, and overall skin firmness.
Profhilo’s results develop gradually, as it works by stimulating collagen and elastin production within the dermal cells. While some patients notice subtle improvements in skin tone and hydration after their first session, significant changes, such as smoother, firmer, and more radiant skin, typically appear six weeks after the initial treatment. The full benefits are achieved after the second session, offering natural, long-lasting rejuvenation.
Proper aftercare is crucial to maximise the benefits of your Profhilo injectable treatment and ensure optimal results. It’s important to avoid touching the treated areas for the first six hours to minimise the risk of infection and allow the skin to settle. Refrain from applying makeup during this time to support natural healing. For 24 hours after your treatment, avoid strenuous exercise, saunas, or UV exposure to prevent irritation or swelling. While mild redness or slight swelling may occur, these effects typically subside within a few days. Following these guidelines helps keep your skin calm and receptive, allowing Profhilo to deliver its full skin benefits, including enhanced hydration, improved elasticity, and firmer, revitalised skin.
Location
PHI Clinic
102 Harley Street,
London,
W1G 7JB,
United Kingdom
Tel: 02070345999
Opening Hours
Monday & Tuesday - 9:30am to 6:00pm
Wednesday & Thursday - 9:30am to 8:00pm
Friday - 9:30am to 5:00pm
Saturday - 11:30am to 12:30pm
Sunday - Closed
Opening times can change, if your appointment is outside of these times please contact the clinic for confirmation.
